2 edition of On the biosynthesis of glycoproteins in the submandibular gland of the rat. found in the catalog.
On the biosynthesis of glycoproteins in the submandibular gland of the rat.
Bibliography: p. 93.
|Series||Arkiv för kami,, bd. 29, nr. 8|
|LC Classifications||QD1 .S923 bd. 29, nr. 8|
|The Physical Object|
|Number of Pages||93|
|LC Control Number||74369758|
Beyer TA, Rearick JI, Paulson JC, Prieels JP, Sadler JE, Hill RL. Biosynthesis of mammalian glycoproteins. Glycosylation pathways in the synthesis of the nonreducing terminal sequences. J Biol Chem. Dec 25; (24)– Barker R, Olsen KW, Shaper JH, Hill RL. SUMMARY: • Glycoproteins are of various types, based on their linkages. • Different types of linkages follow different biosynthetic pathways. • Glycoproteins play diverse roles in various important functions of the body. • A great many of the properties of the glycoproteins are due to the oligosachharide component.
This equine submandibular gland (Tiralongo et al., unpublished) in the case of 4-O-acetylation, as well as in rat liver  and ®nding led to a rapid sequence of publications from various laboratories, mainly of Akemi Suzuki in Tokyo, Ajit Varki in bovine submandibular gland  in the case of 9-O- San Diego and our group, summarized in . The acylation of salivary mucin with fatty acids and its biosynthesis was investigated by incubating rat submandibular salivary gland cells with (/sup 3/H)palmitic acid and (/sup 3/H)proline. The elaborated extracellular and intracellular mucus glycoproteins following delipidation, Bio-Gel P chromatography, and CsCl equilibrium density.
Glycoproteins are accessible to study Glycoproteins occur on cell surfaces and many are actively secreted from cells and are thus relatively accessible to biochemical investigations. Some glycoproteins are amongst the best characterised of proteins, and biochemistry students will undoubtedly have heard of. Development&growth of salivary glands. During fetal life each salivary gland is formed at a specific location in the oral cavity through the growth of a bud of oral epithelium into the underlying mesenchyme d & submandibular_ 6th wk. gual th wk. 3.
The Martian and the supermarket and other stories.
Understanding the New Testament
Private duty nurse
Nutrition and caries.
Suggested series of movies for a course in urban planning.
Duties of literature and arts in our revolution
Personal property leasing
C.R.I.S. case studies for the nineties
Acting in Musical Theatre
Middle childhood/generalist standards for national board certification
K A Barzen's 27 research works with citations and reads, including: Synergistic suppression of apoptosis in salivary acinar cells by IGF1 and EGF. Eleni E. Kousvelari's 39 research works with citations and reads, including: Regulation of Salivary-Gland-Specific Gene Expression.
Abstract. The biosynthesis of enamel matrix components of developing rat incisors was investigated by measuring the incorporation of /sup 3/H-proline, /sup 32/P-phosphate, and /sup 35/S-sulfate in vivo.
/sup 3/H- and /sup 32/P-radioactivity was found in what seemed to be a prototype of enamel proteins. J.J. Geuze and J.W. Slot. Synthesis and secretion of glycoproteins in rat bulbourethral (Cowper’s) gland.
The effect of copulation on the glandular content and on the incorporation of galactose and leucine. Biol. Reprod.
– (). PubMed CrossRef Google ScholarCited by: The distribution of glycoproteins during palatine gland development and the heterogeneous distribution of glycoproteins observed between posterior and anterior sides expand our knowledge of the role of salivary glands in oral function.
In this review, we describe and discuss glycohistochemical observations of the developing rat palatine : Zaki Hakami, Zaki Hakami, Hideki Kitaura, Shiho Honma, Satoshi Wakisaka, Teruko Takano-Yamamoto.
Abstract. Studies on the wide diversity of biological functions performed by soluble and membrane-bound glycoproteins in mammalian tissues have become a major theme in the research of a large number of biochemists and cell biologists, as well as neurochemists. The three major types of glycoproteins present in animal cells, that is, the secretory, lysosomal and plasma membrane glycoproteins, were examined with regard to the sites of synthesis of their carbohydrate side chains and to their subsequent migration within cells.
The site at which a monosaccharide is added to a growing glycoprotein depends on the position of that monosaccharide. The biosynthesis of N-glycolylneuraminic acid is similar to the formation of N-glycolylmuramic acid, which are responsible for the biosynthesis of the oligosaccharide chains of porcine submandibular gland glycoproteins.
Swarm rat chondrosarcoma, and chick limb-bud chondrocytes (Hascall,and see Volume 1. Suzuki, in Comprehensive Glycoscience, Biosynthesis. Roseman established that NeuAc is produced from N-acetylmannosamine and pyruvate by a bacterial mammalian sialic acid synthase produces N-acetylneuraminic acidphosphate from N-acetylmannosaminephosphate and biosynthesis of NeuGc was studied using slices of pig submaxillary gland.
Objectives. Mucins are heavily glycosylated large glycoproteins produced in the salivary glands that contribute to salivary viscosity. This study aimed to characterize age-related changes in mucin production in mouse submandibular salivary gland (SMG). Sialic acids. Sialic acids (Sia) are a blooming and challenging area of research, followed by many laboratories around the world.
These monosaccharides are very diverse in their structure and are constituents of many oligosaccharides, glycoproteins and glycolipids, especially of cell membranes and of secreted products, e.g.
the mucins and milk oligosaccharides. The developmental expression of salivary glycoconjugates was investigated in the rat submandibular and sublingual glands by conventional and lectin histochemistry. chemi cal methods, are bovine submandibular gland [1, 2, 18, 19] and human colon mucosa [ 20–22 ].
The mucins from these tissues are extremely rich in these Sia. The acini of the submandibular gland contain both serous and mucous cells in all three species (Figs. and ). In mice, the gland is mixed mucoserous, rat is mostly mucous with a serous component, and human is typically mixed, with serous cells predominating.
Sialic acids are a family of nine carbon keto-aldononulosonic acids presented at the terminal ends of glycans on cellular membranes. α-Linked sialoglycoconjugates often undergo post-glycosylation modifications, among which O-acetylation of N-acetyl neuraminic acid (Neu5Ac) is the most common in mammalian cells.
Isoforms of sialic acid are critical determinants of virus pathogenesis. In rat SM glands, taurine is suggested to act as a regulator of the saliva ionic strength and, in human saliva, appears to be correlated to physical stress. Our study shows that such metabolite is present in all three types of saliva with a marked prevalence in PS (Table 1 —Section A), thus, suggesting a role in salivary glands function.
View chapter Purchase book. Read full chapter The enzyme has a more restricted acceptor specificity compared to T1 and prefers peptide derived from rat submandibular gland mucin as the acceptor substrate. A ppGalNAc-T4 (Figure 3). 11 The biosynthesis of N-linked glycoproteins is relatively well characterized.
11 The core structure. biosynthesis of the linkage tetrasaccharide, defects in XylT, GalT-II, and glucuronyltransferase-I (GlcAT-I) may result in the same disease,16 GlcAT-I completes the biosynthesis by transferring a GlcA residue to the linkage trisaccharide, GalbGalbXylb1-O-Ser, in the medial- and trans-Golgi compartments (Figure 4),18 Notably, overexpression of GlcAT-I also resulted in the formation.
The incredible ibex defies gravity and climbs a dam | Forces of Nature with Brian Cox - BBC - Duration: BBC Recommended for you. Sialic acids are a family of negatively charged monosaccharides which are commonly presented as the terminal residues in glycans of the glycoconjugates on eukaryotic cell surface or as components of capsular polysaccharides or lipooligosaccharides of some pathogenic bacteria.
Due to their important biological and pathological functions, the biosynthesis, activation, transfer, breaking down. Introduction. To ensure survival and ecological success, animals have to maintain energy demanding processes like metabolism, growth, and reproduction. 1 Therefore, animals have to intake, process, and allocate energy, proteins, and other nutrients.
2 These requirements must be covered by food intake to assure survival. The conversion of food into metabolizable energy occurs in the.biosynthesis of the brain of human and rat newbor ns. Yamakawa or in equine submandibular gland mucin. (and also glycoproteins and gangliosides) contain very small amounts of Kdn as the.(glucose/galactose) while rat sublingual glycoproteins contain as much as 81% carbo- hydrate comprised of D-galactose, D-mannose, L-fucose, N-acetyl-3/-o-hexosamines and sialic acid.
Hence any distinction between different classes of glycoproteins based purely on their carbohydrate content will tend to be arbitrary.